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Joseph A Fraietta Selected Research

Artificial Receptors

1/2022Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing.
1/2018CAR T Cell Therapy of Non-hematopoietic Malignancies: Detours on the Road to Clinical Success.
1/2018Toward precision manufacturing of immunogene T-cell therapies.

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Joseph A Fraietta Research Topics

Disease

24Neoplasms (Cancer)
01/2022 - 01/2014
8B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
11/2022 - 03/2016
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2020 - 03/2016
3Prostatic Neoplasms (Prostate Cancer)
01/2022 - 01/2018
3Glioblastoma (Glioblastoma Multiforme)
10/2021 - 02/2015
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2019 - 01/2018
3Infections
12/2014 - 10/2010
2Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 11/2020
2Disease Progression
01/2019 - 01/2013
2Leukemia
10/2018 - 03/2016
2Multiple Myeloma
01/2018 - 01/2014
1Cytokine Release Syndrome
01/2022
1COVID-19
01/2022
1Sepsis (Septicemia)
01/2022
1Pemphigus (Pemphigus Vulgaris)
12/2020
1Blister (Bulla)
12/2020
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
04/2016
1Fibrosis (Cirrhosis)
04/2016
1Bacterial Infections (Bacterial Infection)
02/2016
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2016
1Acquired Immunodeficiency Syndrome (AIDS)
12/2014
1HIV Infections (HIV Infection)
01/2013
1Inflammation (Inflammations)
10/2010

Drug/Important Bio-Agent (IBA)

19Chimeric Antigen ReceptorsIBA
11/2022 - 01/2014
6AntigensIBA
01/2022 - 01/2014
5Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2014
4ibrutinibIBA
11/2022 - 01/2016
4CytokinesIBA
01/2022 - 01/2013
3Artificial ReceptorsIBA
01/2022 - 01/2018
3VaccinesIBA
03/2021 - 12/2014
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2022 - 01/2018
2Antiviral Agents (Antivirals)IBA
01/2022 - 01/2013
2AutoantigensIBA
12/2020 - 01/2018
2tisagenlecleucelIBA
10/2018 - 01/2016
2Neoplasm Antigens (Tumor Antigens)IBA
01/2018 - 01/2018
2DeoxyriboseIBA
12/2014 - 10/2010
2Anti-Infective Agents (Microbicides)IBA
12/2014 - 10/2010
1Calcineurin InhibitorsIBA
01/2022
1Oxygen (Dioxygen)IBA
01/2022
1Investigational DrugsIBA
01/2022
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2022
1Prostate-Specific Antigen (Semenogelase)IBA
01/2022
1ChemokinesIBA
01/2022
1AntibodiesIBA
03/2021
1p21-Activated KinasesIBA
01/2021
1AutoantibodiesIBA
12/2020
1EpitopesIBA
12/2020
1Desmoglein 3IBA
12/2020
1Immunoglobulin G (IgG)IBA
12/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2019
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2018
1B-Cell Maturation AntigenIBA
01/2018
1acalabrutinibIBA
08/2017
1Matrix Metalloproteinases (MMPs)IBA
04/2016
1Protein Isoforms (Isoforms)IBA
02/2016
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
02/2016
1epidermal growth factor receptor VIIIIBA
02/2015
1Interferon Type IIBA
01/2013
1OligodeoxyribonucleotidesIBA
10/2010
1Toll-Like Receptor 7IBA
10/2010
1Poly TIBA
10/2010

Therapy/Procedure

17Immunotherapy
01/2022 - 01/2014
13Therapeutics
01/2022 - 01/2016
2Drug Therapy (Chemotherapy)
01/2019 - 04/2016
1Castration
01/2022
1Cell- and Tissue-Based Therapy (Cell Therapy)
01/2020